Obesity and Pharmaceuticals

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Future Pharmacotherapy for Obesity: New Anti-Obesity Drugs on the Horizon

This review published in Current obesity reports looks at how our increased understanding of energy regulation and neurohormonal pathways in energy homeostasis (the body’s mechanism for controlling caloric intake and energy expenditure) are being...
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New combination of drugs cause enhanced weight loss

Researchers at the University of Pennsylvania have found that a unique combination of weight loss drugs can have a dramatic effect on laboratory animals. The researchers studied the effect of two different drug classes that affect the hormones amylin...
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T2DM prevented in 80% of at-risk patients

A team from Imperial College London have repurposed the drug liraglutide and have found that it can help to prevent the progression of ‘prediabetes’ to diabetes. Prediabetes itself is characterised by slightly increased blood sugar levels and can...
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Keeping an eye out for medications that can cause weight gain

In a study published in Gastroenterology researchers have urged physicians to be mindful of drugs that can increase weight gain in patients that are already obese. This must be done by evaluating the potential side effects of medications that are prescribed...
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Cancer-fighting drugs help weight loss

Researchers from the Mayo clinic have found that two common anti-cancer drugs have caused significant weight loss in mice. This effect was seen even though the mice continued consuming a high-fat diet. Originally, this research was conducted to address...
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Narcolepsy drugs could help food addicts

Narcolepsy is a sleep disorder that causes people to fall asleep at inappropriate times, and now a recent study has found that a drug that is used in the condition may help food addicts lose weight. Recent evidence has shown that obesity is not just caused...
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New drug treatment for rare genetic disease

A new drug has been shown to be effective in the treatment of a rare genetic disease that leads to obesity. In a paper published in NEJM, Setmelanotide was shown to induce weight loss and reduce appetite in patients with Pro-opiomelanocortin (POMC) deficiency....
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Comparing the effectiveness of weight loss drugs

A recent analysis has compared the effectiveness of the 5 weight-loss drugs that have been approved by the USA’s FDA. These drugs are: orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide. The drugs were compared against...
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