Rising bowel cancer rates in UK youth linked to obesity and alcohol consumption
A recent study has highlighted a concerning trend in the United Kingdom: increasing instances of bowel cancer among younger individuals, driven by unhealthy lifestyle choices. This alarming development is primarily attributed to factors such as obesity, excessive alcohol consumption, and a general lack of physical activity.
Traditionally diagnosed in individuals over the age of 50, bowel cancer is now increasingly affecting younger demographics. This shift coincides with a deterioration in lifestyle habits among the youth, including heightened alcohol consumption and reduced physical exercise. The research, published in the ‘Annals of Oncology‘, raises questions about the adequacy of current screening ages and calls for a re-evaluation.
The study also presents worrying findings regarding bowel cancer mortality rates in women. Unlike many other cancers, which are showing a declining death rate, bowel cancer continues to pose a significant threat to women of all ages. The comparative analysis of anticipated death rates in 2024, using 2018 as a baseline, reveals that the UK is experiencing a notably higher increase in these rates compared to other European countries like Italy, Germany, Poland, and Spain.
Specifically, the UK is facing a projected 26% increase in bowel cancer death rates among men and an even more startling 39% rise among women. These figures starkly contrast with those from other European nations, where the increases, though present, are considerably lower.
Researchers have identified a worrying trend in bowel cancer mortality, especially among the 25 to 49 age group, where rates have been climbing since around the year 2000 in both men and women. This is despite an overall decrease in colorectal cancer mortality across all age groups in past decades.
Interestingly, while the overall cancer death rates in the UK are predicted to decline among both sexes, bowel cancer remains a significant exception, particularly for women. The researchers noted that while age-standardised rates (ASRs) for bowel cancer are showing a favourable decrease for men, the same is not true for women.
Professor Carlo La Vecchia, from the University of Milan, emphasises that key contributors to this rise in young people include obesity, overweight, and associated health issues like elevated blood sugar levels and diabetes. He also points out the link between alcohol consumption and early onset bowel cancer. Countries that have seen a reduction in alcohol consumption, such as France and Italy, have not witnessed such pronounced increases in bowel cancer death rates.
Professor La Vecchia also highlights the aggressiveness of early onset bowel cancer, noting its lower survival rates compared to cases diagnosed in older individuals. He urges national governments to adopt policies promoting healthier lifestyles, including increased physical activity and reduced obesity and alcohol consumption. Furthermore, he advocates for the lowering of the age threshold for bowel cancer screening to 45 years.
The World Cancer Research Fund has labelled these findings as “alarming”, acknowledging the increasing exposure of young people to cancer risk factors from an early age. Dr Panagiota Mitrou, the director of research at the WCRF, underscores the importance of addressing these risk factors early on.
In England, bowel cancer screening is currently offered to individuals aged 60 to 74, with plans to expand the programme to those aged 50 to 59. However, there is a call for further improvements in diagnosis, treatment, and survival rates. Former national cancer director, Professor Sir Mike Richards, suggests adjusting the sensitivity threshold for the FIT stool test to enhance early detection.
Responding to these concerns, a spokesperson for the Department of Health and Social Care emphasised the role of the independent UK National Screening Committee in determining the age cohorts for screening, balancing the benefits against potential harms such as overdiagnosis. They also highlighted the government’s commitment to promoting healthier food choices and tackling obesity, acknowledging its significant impact on the NHS and its contribution to a range of serious diseases.