Ozempic and GLP-1 Drugs Added to WHO Essential Medicines List – What Healthcare Professionals Need to Know
The WHO has added GLP-1 receptor agonists (GLP-1RAs), often referred to as GLP-1 drugs, to its Essential Medicines List. This signals global recognition of their role in treating obesity and type 2 diabetes. From an educational perspective, this is a turning point. It will accelerate patient demand and prescribing opportunities for healthcare professionals worldwide. The question we must now ask is how to best prepare for their safe and effective use.
By Nigel Hinchliffe, CCH Director of Education
Global recognition of GLP-1 therapy
The World Health Organisation has just published its latest Essential Medicines List (EML) – the first since July 2023. One of the most notable new inclusions is GLP-1-based medications (such as Wegovy, Ozempic and Mounjaro) for type 2 diabetes and obesity treatments.
The EML is a list of over 500 medicines that the WHO consider essential to meet priority healthcare needs. These medicines should be available to all, affordable and of assured quality at all times. Medicines are selected based on public health relevance, evidence of benefits and harms, and with consideration of cost and affordability.
Four GLP-1RA drugs are now included in the EML:
- dulaglutide (Trulicity)
- liraglutide (Saxenda)
- semaglutide (Ozempic/Wegovy) and
- tirzepatide (Mounjaro/Zepbound)
Their inclusion confirms what many of you will already have observed in practice: these are no longer fringe therapies, but treatments you must be ready to encounter routinely.
What this means for healthcare professionals
This decision signals global recognition of GLP-1RAs as critical therapies for serious chronic conditions – for treating metabolic disorders. It stands in sharp contrast to the public narrative that too often frames them as cosmetic quick fixes.
For practitioners, this shift will likely be significant. It could mean more time spent answering patient questions, more conversations about eligibility, and in many cases more opportunities to prescribe. In fact, whether you are directly involved in prescribing or working alongside those who are, these changes will affect everyday clinical practice. The challenge is ensuring that you are not only ready to meet demand but also prepared to integrate these medicines safely and thoughtfully into care.
Access and affordability challenges
The inclusion of Ozempic and other GLP-1RA drugs on the WHO list of Essential Medicines also raises questions of equity. Will these medicines be available and affordable for people living with obesity and type 2 diabetes worldwide?
At present, access remains limited. In the private sector, costs and supply constraints limit use. On the NHS, access is further restricted by the tight eligibility criteria set by NICE.
But change is coming. Cost and supply barriers are likely to ease over the next few years, as patents expire and generic versions become available. For example, liraglutide’s European patents are due to expire in 2026, with dulaglutide following in 2027–2028. The WHO’s decision should encourage governments to prepare, influencing policies, funding and procurement to improve availability and access.
For the UK, this could be transformative. Increased availability and lower costs may prompt NICE to broaden eligibility, enabling wider GLP-1RA prescribing on the NHS. For those of us working in education, this presents both an opportunity and a responsibility: ensuring professionals are supported to use these therapies well.
Wider access would also bring system-wide benefits, since preventing complications of obesity and diabetes – from cardiovascular disease to cancer and liver disease – is both clinically sound and economically sensible.
For healthcare professionals, the question is not whether you will encounter these drugs, but how ready you will be to use them well.
Preparing for safe GLP-1RA prescribing
Recent media reports of people obtaining GLP-1RA drugs from private clinics, or even the black market, without adequate medical oversight show the risks of uncontrolled use. This has already led to poor outcomes and, in some cases, serious emergencies.
The WHO’s decision to classify these medicines as essential has the potential to change this picture. By embedding GLP-1RA prescribing within NHS pathways, particularly in NHS primary care, people living with type 2 diabetes and/or obesity will gain access to GLP-1RA therapy within structured, long-term, multi-modal care. But it also raises the stakes: safe prescribing depends on practitioners having the right preparation and confidence.
Many frontline healthcare professionals will need additional support to build this knowledge and confidence. These drugs were traditionally confined to diabetes management pathways. Their use in weight management and obesity care requires careful attention to contra-indications, side-effect management, dose optimisation, and integration with diet and lifestyle support.
Targeted education is one of the most effective ways to bridge this gap. High-quality CPD can equip you with the knowledge and skills to prescribe responsibly or to contribute meaningfully to treatment planning, even if you are not prescribing directly. For those seeking a practical starting point, CCH’s online course GLP-1RAs in Focus – Why Drugs Like Ozempic Work, offers a clear, evidence-based introduction in just two hours.
Looking ahead to 2026
Next year 2026, could mark a turning point in obesity and diabetes care. Recognition of GLP-1RA medications as essential medicines, combined with greater availability, will almost certainly increase both prescribing opportunities and patient demand.
As an educator, I see this as a moment to prepare. For healthcare professionals, the question is not whether you will encounter these drugs, but how ready you will be to use them well. By strengthening your knowledge and skills now, you will be best placed to meet the challenge – and to support patients in making the most of this new phase in care.
FAQs: Ozempic, GLP-1 drugs, and the WHO Essential Medicines List (2025)
Why did WHO add GLP-1 drugs to the Essential Medicines List?
The World Health Organisation (WHO) reviews medicines for the Essential Medicines List based on public health relevance, evidence of benefit, safety, and cost-effectiveness. GLP-1 receptor agonists, such as semaglutide and tirzepatide, were added in 2025 due to strong evidence that they improve outcomes in people with type 2 diabetes and obesity, reducing cardiovascular risk as well as supporting weight management and improving blood sugar control.
Which GLP-1 drugs are included on the WHO list?
The 2025 Essential Medicines List includes dulaglutide (Trulicity), liraglutide (Saxenda/Victoza), semaglutide (Ozempic/Wegovy), and tirzepatide (Mounjaro/Zepbound). These medicines were selected for their efficacy, safety, and potential to address the global burden of obesity and type 2 diabetes.
What does this mean for NHS access to GLP-1 therapies?
In the UK, NHS access to GLP-1 drugs is currently restricted by NICE eligibility criteria and supply limitations. The WHO decision does not directly change NHS policy, but it is likely to influence future guidance. As costs fall with the arrival of generic versions from 2026 onwards, NICE may broaden eligibility, making these treatments more widely available.
Are GLP-1 drugs safe for all patients?
GLP-1 therapies are effective but not suitable for everyone. Contra-indications include a history of certain endocrine conditions, while gastrointestinal side effects such as nausea are common during dose escalation. Safe prescribing requires clinical assessment, careful monitoring, and support with diet and lifestyle changes. This is why training and professional education are vital for healthcare providers.
Quick Links
Find the 2025: WHO Model List of Essential Medicines here.
Find a clear, evidence-based intro to GLP-1 drugs with the online course. Click here to explore GLP-1RAs in Focus – Why Drugs Like Ozempic Work.
About the Author
This article was written by Nigel Hinchliffe, Director of Education at the College of Contemporary Health (CCH). Nigel has extensive experience in clinical education, with a particular focus on obesity care and the safe integration of new therapies into practice. At CCH, he leads the development of evidence-based training programmes that support healthcare professionals in delivering high-quality, patient-centred care.
