Adolescent stress linked to adult obesity and hypertension

Recent research indicates a strong correlation between high stress levels experienced during adolescence and the subsequent development of cardiometabolic risk factors, such as obesity and hypertension, in adulthood.

Published in the Journal of the American Heart Association, this study underscores the necessity of implementing stress management techniques from an early age. These strategies are vital in reducing the likelihood of health issues later in life, including heart disease and Type 2 diabetes.

Dr. Fangqi Guo, the lead author of the study and a postdoctoral research fellow at the University of Southern California’s Keck School of Medicine, emphasises the significance of understanding how stress perceived from childhood impacts the escalation of cardiometabolic risk factors in young adults. Dr. Guo’s findings reveal that long-term stress perception significantly influences various cardiometabolic aspects such as fat distribution, vascular health, and obesity. He stresses the importance of adopting stress management practices during adolescence to safeguard health.

Cardiometabolic risk factors, encompassing obesity, Type 2 diabetes or prediabetes, high cholesterol, and hypertension, often co-occur and are major contributors to cardiovascular disease. In 2020, cardiometabolic diseases, including cardiovascular conditions and Type 2 diabetes, were leading chronic health issues in the U.S., accounting for approximately 25% of all deaths, as per the American Heart Association.

The American Heart Association’s 2017 report highlighted that childhood adversities have long-term effects on cardiometabolic health. In recent decades, perceived stress has also been increasingly recognised as a contributing factor to cardiometabolic health problems.

In this new investigation, researchers analysed data from 276 individuals participating in the Southern California Children’s Health Study. The participants, initially enrolled by their parents between 2003 and 2014 at an average age of six, underwent health assessments during adolescence and as young adults from 2018 to 2021. Their average ages during these assessments were 13 and 24 years, respectively.

Each assessment included responses to a four-item Perceived Stress Scale, a widely utilised method for assessing stress-related feelings and thoughts over the previous month. For the youngest participants, stress levels were reported by their parents. The participants were then categorised into four groups based on their stress patterns: consistently high, decreasing, increasing, and consistently low.

The study’s evaluation of cardiometabolic health involved various health measurements, such as blood pressure and weight. Researchers also examined neck artery thickness to assess blood flow, haemoglobin A1C levels to determine diabetes status, and body fat percentage, with a focus on abdominal fat, a known risk factor for cardiovascular disease and Type 2 diabetes.

Participants who reported higher stress levels from their teenage years into adulthood were more prone to high blood pressure, increased total body fat, more abdominal fat, poorer vascular health, and a higher risk of obesity than those who experienced lower stress levels.

Dr. Guo expressed surprise at the consistency of the association between perceived stress patterns and various risk factors. He advocates for healthcare professionals to incorporate the Perceived Stress Scale in clinical assessments, allowing for early identification and treatment of individuals with elevated stress levels.