A lot of resources that are available for healthcare professionals (HCPs) are outdated, too commercial, and lack trust from the HCP community. But there are some hidden gems however, especially concerning the fields of modern health conditions, that we believe will be beneficial for those who utilise them.
Have you ever wanted somewhere other than Facebook to communicate with...Read More
In this paper, published in The Lancet, the authors sought to assess efficacy and safety of the glucagon-like peptide-1 (GLP-1) analogue semaglutide, in comparison with a similar drug liraglutide, and placebo. The study was done in 8 countries, involving 71 clinical sites, with the primary endpoint being weight loss at week 52.
GLP-1 analogues mimic the function of human GLP-1, which...Read More
Cellular metabolism is a chain reaction of steps, controlled and aided by enzymes, which leads to the production of molecules that the cell requires. An important family of metabolites, called ceramides, are known to have an important role in cell signalling and apoptosis, as well as other physiological functions
In this study published in Nature, the researchers tested a new selective enzyme...Read More
Obesity is simply caused by an imbalance in energy consumed and calories burned, however what causes this imbalance is complex and multifactorial. If enough calories are burned through physical activity, then an individual should not gain weight. Following this rationale, if an environment is more conducive to exercise then an individual is less likely to be overweight. This argument is the...Read More
In some patients, weight-loss guidelines recommend the use of pharmacological agents as adjuncts to lifestyle modification. Although not many are licensed, they have been shown to be effective for long-term weight management. One of the serious downsides of these drugs is the side-effects. Depending on their sight of action, they have been known to precipitate severe complications in the...Read More
Obesity is known to be associated with an increased risk of several major non-communicable diseases including type-2 diabetes, coronary heart disease, stroke, asthma and several cancers. It was previously thought that metabolically healthy obese (MHO) individuals were at no increased risk of these conditions. MHO is characterised by a healthy blood pressure, low cholesterol, normal insulin...Read More
Epidemiological studies have previously demonstrated the contribution of a genetic background of diabetes to the development of obesity. The goal of this study was to explore the contribution of parental family history of diabetes to visceral fat area. Diabetes and obesity share many overlapping risk factors and genetic architecture, with visceral fat being responsible for many of the...Read More